(R)-3,3′-Dibromo-[1,1′-Binaphthalene]-2,2′-diol

(R)-3,3′-Dibromo-[1,1′-Binaphthalene]-2,2′-diol - Names and Identifiers

Name	(R)-(+)-3,3-Dibromo-1,1-bi-2-naphtol
Synonyms	(R)-Dibromo-BINOL (R)-Dibromo-bi-2-naphthol (R)-Dibromo-1,1-Binaphthol (R)-Dibromo-1,1′-Bi-2,2′-naphthol (R)-3,3-Dibromo-1,1-bi-2-naphthol (R)-3,3'-Dibromo-1,1'-Bi-2-Naphthol (R)-(+)-3,3-Dibromo-1,1-bi-2-naphtol (R)-(+)-3,3'-Dibromo-1,1'-Bi-2-Naphthol (R)-(+)-3,3'-Dibromo-1,1'-bi-2-naphthol (R)-Dibromo-1,1′-Binaphthalene-2,2′-diol 3,3'-dibromo-1,1'-binaphthalene-2,2'-diol (R)-3,3'-Dibromo-2,2'-Dihydroxy-1,1'-Binaphthyl (R)-3,3′-Dibromo-[1,1′-Binaphthalene]-2,2′-diol 3-bromo-1-(3-bromo-2-hydroxy-1-naphthalenyl)-2-naphthalenol
CAS	111795-43-8
InChI	InChI=1/C20H12Br2O2/c21-15-9-11-5-1-3-7-13(11)17(19(15)23)18-14-8-4-2-6-12(14)10-16(22)20(18)24/h1-10,23-24H

(R)-3,3′-Dibromo-[1,1′-Binaphthalene]-2,2′-diol - Physico-chemical Properties

Molecular Formula	C20H12Br2O2
Molar Mass	444.12
Density	1.761±0.06 g/cm3(Predicted)
Melting Point	256-260°C
Boling Point	469.9±40.0 °C(Predicted)
Specific Rotation(α)	+43° (c 0.22, CHCl3)
Flash Point	238.012°C
Solubility	within almost transparency in Methanol
Vapor Presure	0mmHg at 25°C
Appearance	White to brown powder or crystalline or lumpy
Color	White to pale yellow-beige
pKa	6.43±0.50(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.779
MDL	MFCD03093629

(R)-3,3′-Dibromo-[1,1′-Binaphthalene]-2,2′-diol - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S37/39 - Wear suitable gloves and eye/face protection
UN IDs	UN 3077 9 / PGIII
WGK Germany	3
HS Code	29081990

(R)-3,3′-Dibromo-[1,1′-Binaphthalene]-2,2′-diol - Introduction

(R)-(+)-3,3 '-dibromo-1, 1'-bis-2-naphthol, abbreviated as (R)-BINOL, is an organic compound. It has the following properties:

1. Appearance:(R)-BINOL exists in the form of white to pale yellow crystals.
2. Solubility: It has low solubility in non-polar solvents (such as alkanes) and high solubility in polar solvents (such as alcohols or ketones).
3. melting point: about 105-110 degrees Celsius.

(R)-BINOL is widely used in the field of organic synthesis, mainly for asymmetric synthesis reactions, such as the synthesis of chiral catalysts. It has good chiral induction properties and can be used as a catalyst for asymmetric oxidation, reduction and substitution reactions. For example, it can catalyze the synthesis of asymmetric ring compounds.

There are many ways to prepare (R)-BINOL, one of which is commonly used by reacting naphthalene with hydrogen bromide and then reducing it.

Regarding safety information, the following should be noted when storing and using (R)-BINOL:

1. Because (R)-BINOL is an organic compound, keep it away from fire sources and maintain a well-ventilated environment during storage and operation.
2. When carrying and operating (R)-BINOL, wear appropriate personal protective equipment, such as lab gloves, goggles and lab clothes.
3. Avoid direct contact of (R)-BINOL with skin, eyes and mouth.
4. In case of accidental exposure to (R)-BINOL, immediately rinse the eyes or skin with clean water and seek medical attention immediately.
5. When disposing of (R)-BINOL waste, it should be disposed in accordance with local environmental regulations.

When using (R)-BINOL for experiments, follow relevant safety procedures and follow the guidelines for the safe use and handling of chemicals.

Last Update：2024-04-09 21:21:28